Restore circulatory volume and monitor fluid balance and overall clinical status closely. No study discussed in detail the strategy used to transition from NG feeds back to an oral diet. 1Southampton University Hospital NHS Trust, Southampton SO16 6YD, 2Royal Bournemouth Hospital, Bournemouth, Dorset BH7 7DW. Anorexia nervosa. old, P<0.05 [37] and 20% in early onset AN compared to 0% in adult onset AN P<0.05 [43]). Prior to 2017, St Georges Hospitals refeeding guidelines (Figure 2/Figure 3) were not in line with NICE's Nutrition Support for Adults guidelines (CG32). This audit included patients from January November 2017 whereby 51 patients were identified as high risk or extremely high risk and 3 were classed as at risk. However, this new definition may be insufficiently specific for clinically relevent electrolyte changes and requires clinical validation. Significant discrepancy (>700 calories) was noted between nurse-estimated caloric intake compared to digital images. study [18] in a medical ward (where NG was implemented due to insufficient oral intake) discussed NG feeding in the context of YP with more severe medical problems, (such as intractable vomiting and superior mesenteric artery syndrome) which therefore took longer to transition to oral diet, resulting in a longer admission. https://doi.org/10.5694/j.1326-5377.2009.tb02487.x. Our unpublished survey of doctors, nurses, pharmacists, and dietitians (all members of their respective nutrition societies) on their attitudes to the guidance from the National Institute for Health and Clinical Excellence (NICE)2 showed widespread disparities in practice. It seems logical to avoid administering insulin if possible (e.g., allowing glucose to rise to ~200-300 mg/dL). Consequently, the reported incidence rates varied between 0% and 80% depending on the definition and the population studied [2,8]. In the subgroup analyses, inpatients from Intensive Care Units (ICUs) and those initially fed with >20kcal/kg/day seemed to have a higher incidence of both RFS (pooled incidence=44%; 95% CI 36%52%) and RH (pooled incidence=27%; 95% CI 21%34%). This causes insulin secretion to increase. Compared to other mental illnesses, EDs have a high mortality rate with young people (YP) with anorexia nervosa (AN) on average 610 times more likely to die than the general population [4, 5]. EMCrit is a trademark of Metasin LLC. By using this website, you agree to our BMJ Open. There are currently over 700,000 individuals in the UK with an eating disorder (ED) [1]. McCray S, et al. Inpatients were prospectively enrolled. Skeletal muscle index (SMI), quantifying muscle mass, was assessed with computed tomography (CT) in 98 patients undergoing esophagectomy. Youve lost more than 10 percent of your body weight in the past 3 to 6 months. Previous reviews [32, 33] have examined use of NG feeding in ED, including the safety and efficacy of NG feeding as well as short-term and long-term outcomes. Refeeding syndrome results from underfeeding for a period of time, followed by re-initiation of nutritional support (including enteral nutrition, parenteral nutrition, or even IV dextrose). Robb et al [39] compared nocturnal NG feeding to supplement oral diet (maximum 3255 kcals /d) with oral intake (max 2508 kcals/d) reporting nocturnal NG feeding weight gain of 5.4kgs versus 2.4kgs in the oral diet only group. Kristen Hindley. Nutritional rehabilitation is central to achieving medical stabilization. WebIv or oral multivitamins once daily for 10 days or greater based on clinical status Emad Zarief 2021 29 ASPEN Consensus recommendations for refeeding syndrome. Best C. How to set up and administer an enteral feed via a nasogastric tube. 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Studies using bolus feeds stated that oral intake was encouraged and it was only when this was not fully achieved that supplementary NG was used [39]. 58% of the studies included only examined the effect of NG feeding as a secondary outcome of their study. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Three studies reported weight gain in the context of inadequate oral intake [9, 18, 39]. Int J Eat Disord. As a library, NLM provides access to scientific literature. Inconsistent study results are partly caused by varying cut-off values used for defining sarcopenia. Start vitamin B12 (cyanocobalamin) 1,000 micrograms PO daily. https://doi.org/10.24953/turkjped.2016.06.010. Short-term outcomes of the study of refeeding to optimize inpatient gains for patients with anorexia nervosa: a multicenter randomized clinical trial [published online ahead of print October 19, 2020]. This exploratory study is based on the data from the Supplemental Parenteral Nutrition study 2 (SPN2), which measured EGP and GNG at days 4 and 10 in 23 critically ill patients. The subjects at risk of developing RFS are characterized by reduced insulin secretion and increased glucagon release, with a metabolic shift towards the utilization as energy sources of proteins and fats instead of glucose with resulting muscle mass loss, and a decrease in intracellular vitamins and minerals, particularly phosphate, potassium, and magnesium, due to undernutrition [4]. modulation of insulin and nutrition. The importance of the refeeding syndrome. Van Noort BM, Lohmar SK, Pfeiffer E, Lehmkul U, Winter SM, Kappel V. Clinical characteristics of early onset anorexia nervosa. The above became the aim of this study. PubMed, Embase, Cochrane Library, Web of Knowledge, and two Chinese databases were systematically searched until October 2021. Results have shown that NG feeding is used commonly in the hospital setting to treat medical instability as a result of severe malnourishment, and in the specialist eating disorders (ED) unit due to failure to meet oral intake. In studies where continuous NG was provided, YP were sometimes not given the option of an oral diet so that their calorie intake could be closely monitored [22,23,24, 31]. 3729-3740, Clinical Nutrition, Volume 40, Issue 6, 2021, pp. 2021 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. Start thiamine prophylactically (e.g., thiamine 100-200 mg IV q12-q24hr). Two studies [37, 43], found NG feeding was more likely to be required in: patients of a lower age at admission (14.3years compared to 15.3yrs. Does aggressive refeeding in hospitalized adolescents with anorexia nervosa result in increased hypophosphatemia? Royal Collage of Psychiatry. Perhaps carbohydrates should initially be limited to <40% of the total energy intake. Eur J Clin Nutr. Giovannino Ciccone: Visualization, Writing - Review & Editing, Supervision. Cumulated insulin dose between days 5 and 9 was correlated to EGP at day 10 (R=0.55, P=0.03). Refeeding syndrome symptoms and warning signs typically appear early in the refeeding process, and require immediate medical intervention upon observation. Effectiveness of assisted reproductive technology. From hospital unit to intestinal failure center: Twenty years of history, The goldilocks problem: Nutrition and its impact on glycaemic control. Marianna Pellegrini: Data curation, Writing - Review & Editing. The refeeding syndrome (RFS) is described as a set of metabolic and electrolyte alterations occurring as the result of the reintroduction of calories through oral, enteral, parenteral nutrition after a period of consistent reduction of energy intake or starvation in individuals with pre-existent malnutrition and/or in a catabolic state [ [1], This preliminary exploratory study shows that GNG and EGP have different predictors on days 4 and 10; EGP is more correlated with the metabolic level, while GNG is dependent on external factors. Home parenteral nutrition (HPN) is one of the most demanding medical therapies as it is the only option for patients for intestinal failure (IF). Further research is warranted to determine whether refeeding syndrome prolongs the length of stay, and to verify the effect of different energy intakes during refeeding on the length of stay in people with malnutrition. Nehring and colleagues [37] concluded that NG feeding had no impact on growth, recovery or development of psychiatric co-morbidities. 3677-3687, Clinical Nutrition, Volume 40, Issue 6, 2021, pp. It is necessary to adapt to the changing circumstances. Fabrizio Pasanisi: Visualization, Writing - Review & Editing. https://doi.org/10.1017/S0033291714001573. Preventative therapies: Thiamine 100-200 mg q12-24. Globally studies from North America [18, 21, 39, 41] and Turkey [36] focused on medical instability in YP with ED. A secondary care hospital in rural India serving a highly tuberculosis (TB) and malnutrition endemic region. https://doi.org/10.1016/j.jadohealth.2013.06.005. 2019;34(3):35970. Table1 includes a summary of included studies. We therefore advocate septic screening and a low threshold for broad spectrum antibiotic cover for any patients with unexplained hypothermia, hypoglycaemia, and evidence of malnutrition. Search strategies combined keywords with controlled vocabulary terms (MeSH, Thesaurus); both quantitative and qualitative research were included. https://doi.org/10.1097/00004703-200412000-00005. If this is tolerated, continue to gradually increase intake up to full nutritional support. Normalization of weight can reverse nearly all of the general medical sequelae of the underweight state, with the exception of bone health [ 3-5 ]. Maginot TR, Kumar MM, Shiels J, Kaya W, Rhee KE. However, this will be the first systematic review on the use of NG feeding specifically in YP with ED. Int J Adolesc Med Health. Eur Child Adolesc Psychiatry. The majority also had a relatively small sample size, again introducing the possibility of bias and reducing generalizability. Patients with RH underwent further evaluation for RFS-associated findings. NG feeding involves a fine bore tube passed via the nasal passage into the stomach in order to administer nutrition. https://doi.org/10.1515/ijamh-2014-0078. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Extended period NPO (>5 days). ;2020 2020 Predict the risk Obtain Caloric goal needs in 3-7 days Emad Zarief 2021 30 Editor's Notes CRRT Continuous R. R. therapy, ED emergency department Between admission and discharge, Parker et al [24] reported a mean overall weight gain of 7.4kgs, Kezelman 2018 [26] reported a mean overall increase of 3.04kg/m2 BMI; Madden et al [25] reported a mean weight gain of 2.79 kgs during medical instability using continuous NG feeding at 2400 kcals per day. Web[34][35][36] Multiple studies apply or recommend the classification of refeeding risk according to the NICE criteria. Aust N Z J Psychiatry. 167 (prepared by the Duke University evidence-based practice center under contract no. The risk for developing refeeding syndrome correlates directly with the extent of weight loss that accompanies anorexia nervosa. We investigated the occurrence of early RFH, its association with clinical outcome, and the impact of early parenteral nutrition (PN) on the development of early RFH in pediatric critical illness. In the UK, three studies described NG use during medical instability after oral intake was refused [27, 28, 40] and one where oral intake was inadequate [31]. J Dev Behav Pediatr. JAMA Pediatr; doi: 10.1001/jamapediatrics.2020.3359Investigators from multiple Overall, this review found 5 studies [9, 18, 23, 24, 29] reported some incidence of electrolyte disturbance, 2 studies [29, 39] described epistaxis and 1 study [39] described behavioural problems associated with the procedure. of 18.5% and 29.9%. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. Baseline demographic, comorbidity and preadmission caloric data were collected. An Australian study [45] (conducted in a paediatric unit) found YP viewed being NG fed as: an unpleasant experience, a necessary intervention, a psychological signifier of illness, and an emphasis in an underlying struggle for control. Routine NG feeding may allow greater initial caloric intake, which does not increase risk of medical complications, and may actually increase initial weight gain thus reducing time in hospital. However, it typically follows a period of: Certain conditions may increase your risk for this condition, including: Certain surgeries may also increase your risk. For more information about refeeding syndrome symptoms and warning signs, contact us. However, due to the high heterogeneity of data, summary incidence measures are meaningless. Encephalitis. If you're underweight and looking to gain weight, it's very important to do it right. Twenty-nine studies met the full criteria. Therefore, the present systematic review and meta-analyses aimed to estimate the incidence of RFS in adults by considering the definition used by the authors as well as the recent criteria proposed by the ASPEN consensus (when applicable). Length of stay was reported in studies from medical and MH ward settings, however, the specific package of treatment YP received in each study was different depending on the country of origin. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. 2020;34:3341. Risk of refeeding was correctly identified and NICE guidelines were adhered to with commencement of feeding at 5kcal/kg/day and appropriate replacement of thiamine and complex vitamin B. Background. 2016;49(3):293310. (2014). Iolanda Cioffi: Conceptualization, Data curation, Methodology, Writing- Original draft preparation, Writing - Review & Editing. Available from: https://www.ncbi.nlm.nih.gov/books/NBK436876/. Predictive factors of length of inpatient treatment in anorexia nervosa. Eating Disorders: Recognition and Treatment. Exclusion terms: psychiatric disorders other than eating disorders; non-primary research; no outcomes specific to NG feeding and participants over 18years. RH was found in 37% (10/27). Hay AP, Chinn D, Forbes D, Madden S, Newton R, et al. Refeeding syndrome can affect anyone. People who are at risk of heart-related complications may require heart monitoring. This systematic review sets out to describe current practice of NG in young people with eating disorders. A team with experience in gastroenterology and dietetics should oversee treatment. Med J Aust. WebThiamine Supplementation in Treatment of Refeeding Syndrome 39 for refeeding syndrome, 100 mg of thiamine is METHODS recommended before initiating feeding or IV uids and 100 mg/day for 5 to 7 days or longer Given the paucity of data on thiamine in patients with severe starvation, chronic supplementation and refeeding syndrome, a As per NICE guidelines, the care plan developed for each patient should specify how the patient will be discharged and reenter community-based care. Most EDs will be treated in an outpatient setting with hospitalisation generally reserved for those with severe malnutrition resulting in physical symptoms such as bradycardia, hypotension or dehydration as set out in the MARSIPAN guidance [16]. Effect sizes were expressed as 95% confidence intervals (CIs) and calculated using random-effects models. NG feeding is a safe and efficacious method of increasing total calorie intake by either supplementing oral intake or continuously. Neiderman M, Farley A, Richardson J, Lask B. Nasogastric feeding in children and adolescents with eating disorders: toward good practice. CF performed the discussion. This review aims to assess strategies for the use, tolerance and effectiveness of NG feeding in YP with restrictive ED. Silber TJ, Robb AS, Orrell-Valente JK, Ellis N, Valadez-Meltzer A, Dadson MJ. Agostino H, Erdstein J, Di Meglio G. Shifting paradigms: continuous nasogastric feeding with high caloric intakes in anorexia nervosa. NG under restraint was described as causing distress and risk of injury to both staff and YP [48]. No ethical approval or consent to participate required due to the nature of the study. Family-based treatment (FBT) is a psychotherapy shown to be effective in a number of randomized controlled trials in physically stable patients with anorexia nervosa (AN), under the age of 19, and within 3 years of illness. What Is Imitation Crab and Should You Eat It? Certain conditions, such as anorexia nervosa or chronic alcohol use disorder, can increase risk. Unfortunately, owing to the high heterogeneity of data, summary incidence measures are meaningless. In the present review, we concluded that higher initial calorie intake may help shorten the length of stay in patients with malnutrition. Provided by the Springer Nature SharedIt content-sharing initiative. It offered the unique chance to present how to create and grow the IF center, increasing the quality of care. Together, these processes can lead to decreased concentrations of minerals in the blood, of which hypophosphatemia is the most characteristic [14]. A subset of patients receiving high glucose nutrition under IO were persistently hyperglycaemic, indicating patient-specific glucose tolerance. Couturier J, Mahmood A. 2 of these studies [24, 26] for the first 2472h started with continuous NG feeding, using higher than standard calorie protocols, 24003000kcal per day prevented any initial drop in weight. You may be at risk if one or more of the following statements apply to you: You may also be at risk if two or more of the following statements apply to you: If you fit these criteria, you should seek emergency medical care immediately. The most common symptoms are as follows: Unfortunately, there is no uniform definition of refeeding syndrome. This systematic review sets out to review the current reported evidence of NG in young people. Paccagnella A, Mauri A, Baruffi C, Berto R, Zago R, Marcon ML, et al. For patients with the highest risk of refeeding syndrome, starting with 5 kcal/kg/day might even be considered (e.g., for a patient with BMI <14 kg/m2 and no nutritional intake for two weeks). (1) Cessation of nutrition followed by refeeding. Refeeding syndrome is caused by sudden shifts in the electrolytes that help your body metabolize food. (2008). 27 patients were enrolled. Skipper. between 7.8% and 23.4% (minimal and maximal error), and GNG at day 10 (age, mean and basal blood glucose), with an e.c. 3807-3814, Indian Journal of Tuberculosis, Volume 67, Issue 2, 2020, pp. 2016;28(1):97105. For survival analysis, log-rank test and Cox proportional hazards regression modeling were used. This appeared to be either after each meal, at set times during the day or once in the evening [27]. In addition, refeeding often occurs alongside other serious conditions that typically require simultaneous treatment. OConnor G, Nicholls D, Hudson L, Singhal A. Refeeding Low Weight Hospitalized Adolescents With Anorexia Nervosa: A Multicenter Randomized Controlled Trial. Rhabdomyolysis can occur (causing an elevated creatinine kinase). Kezelman S, Crosby RD, Rhodes P, Hunt C, Anderson G, Clarke S, et al. WebRefeeding syndrome consists of metabolic changes that occur on the reintroduction of nutrition to in those who are malnourished or in the starved state (Figure 1). Patients from ICU and those who were initially fed with more than 20kcal/kg/day showed a higher incidence of RH and RFS. All rights reserved. (2009). Aggressive repletion of electrolytes, with the exception of calcium (IV calcium may exacerbate hypophosphatemia). Sodium (salt) replacement may also be carefully monitored. No study reported a YP developed RS. WebThe current NICE guidelines poorly predict the occurrence of RH, and modification is likely beneficial. The anabolic processes require minerals and coenzymes such as thiamine [4,6]. As a result, people at risk require medical supervision at a hospital or specialized facility. The PRISMA flowchart was used (Fig. However, further research is required to assess the optimum NG feeding regime for YP at different levels of RS risk. Background The incidence of refeeding syndrome (RFS) in critically ill patients is high, which is detrimental to their prognoses. 3708-3717, Clinical Nutrition, Volume 40, Issue 6, 2021, pp. Research on NG feeding in YP has tended to focus on the acute refeeding phase in paediatric or psychiatric wards to reduce the risk of RS [17]. Isner JM, Roberts WC, Heymsfield SB, Yager J. Anorexia nervosa and sudden death. This is a secondary analysis of the PEPaNIC randomized controlled trial (N=1440), which showed that withholding supplemental parenteral nutrition (PN) for 1 week (late-PN) in the pediatric intensive care unit (PICU) accelerated recovery and reduced new infections compared to early-PN (<24h). 1). A survey of dietitians found 82% considered NG feeding a necessary procedure if oral diet is inadequate [10]. Higher caloric refeeding is safe in hospitalised adolescent patients with restrictive eating disorders. While there is no single definitive marker to identify which patients will develop refeeding syndrome, the National Institute for Health and Clinical Excellence (NICE) has published two sets of criteria for identifying patients at heightened risk for this complication. This has resulted in a variety of NG feeding practices across different settings, with many medical wards tending to provide continuous NG feeds and cease oral intake in order to medically stabilise the patient [20, 22,23,24,25,26]; in contrast mental health wards or specialized eating disorder programs housed on medical wards may be more likely to use syringe bolus feeds to provide food when meals are refused, encouraging oral intake and aiding normalisation of eating [9, 18, 27,28,29,30,31]. Web1 Identification of Refeeding Syndrome Risk 2 Nutritional Care Planning for patients deemed at risk of Refeeding Syndrome 3 Medical advice regarding electrolyte and Shifts in electrolyte levels can cause serious complications, including seizures, heart failure, and comas. A total of 1247 patients were eligible (618 early-PN, 629 late-PN). PubMed Central JM was responsible for references and editing. Refeeding Syndrome: Prevention and Management Sydney Childrens Hospital Practice, Guideline June 2013 Crook MA. When individuals who are at risk are identified early, treatments are likely to succeed. 11 Historically, recommendations for nutritional rehabilitation in inpatient settings have been conservative, 12 16 for fear of precipitating the refeeding syndrome, a constellation of electrolyte disturbances and multiorgan dysfunction that can develop early in the All rights reserved. 2 studies [21, 47] examined male only cohorts but both were high risk of bias. (NICE Guideline, No. This phenomenon is therefore also known as refeeding hypophosphatemia (RFH) [1517]. Any discussion on the risks of the refeeding syndrome should include the increased threat of infection that may often be silent in malnutrition.1 Malnourished patients may develop infection without showing the usual septic markerssuch as an increased temperature, leucocyte count, or C reactive protein. Despite this, the patient encountered refeeding syndrome with significant electrolyte Nocturnal nasogastric refeeding for hospitalized adolescent boys with anorexia nervosa. 2016;31:6819. A brief historical perspective has been added to better illustrate the center's growth and transformation. Int J Eat Disord. WebRefeeding Syndrome NICE guidance (CG32) recommends that for people identified as being at high risk of developing refeeding syndrome, the following should be provided immediately before and during the first 10 days of reintroducing feeding only: oral thiamine 200-300 mg daily vitamin B compound strong 1 or 2 tablets, three times a Conversely the YP in Paccagnella and colleagues [20] research stated NG was helpful, particularly initially when an oral diet was challenging to manage. Maginot et al., 2017 [18] and Whitelaw et al., 2010 [9] reported NG bolus feeding in 13.8 and 15% in order to supplement oral diet with a mean weight gain of 3.1kgs and 2.6kgs respectively but did not report if this was specific to NG feeding. Healthcare professionals can prevent complications of refeeding syndrome by: Refeeding syndrome appears when food is introduced too quickly after a period of malnourishment. 2010;46(6):57782. However, if the analysis was adjusted for confounders, e.g., Charlson Comorbidity Index, no relevant association regarding long-term survival was detected. Though some people who are at risk dont develop symptoms, theres no way to know who will develop symptoms before beginning treatment. Mehanna HM, Moledina J, Travis J. Refeeding syndrome: what it is, and how to prevent and treat it. This review describes the large differences in the use of NG for YP with ED in medical and psychiatric wards in a number of countries globally. Moreover, for clinicians, there is currently conflicting guidance on how to manage NG feeding in YP with ED, in particular how and when to transition between oral and NG feeding [20, 21]. Strik Lievers L, Curt F, Wallier J, Perdereau F, Rein Z, Jeammet P, et al. Cells need electrolytes like phosphate to convert glucose to energy, but phosphate is in short supply. WebIf the patient is considered to be at high risk of refeeding syndrome, the following steps are advised by NICE:1 Start nutrition support at a maximum of 10 kcal/kg/day, increasing levels slowly to meet or exceed full needs by four to seven days. Neiderman M, Zarody M, Tattersall M, Lask B. Enteric feeding in severe adolescent anorexia nervosa: a report of four cases. Conversely, Akgul and colleagues [36] described a much shorter average time, 2.5days, that YP required NG before transitioning to an oral diet. Our review aimed to explore the effects of refeeding syndrome and initial calorie intake on the length of stay in patients with malnutrition. JPEN J Parenter Enteral Nutr. The aim of this systematic review and meta-analyses was to estimate the incidence of RFS in adults by considering the definition used by the authors as well as the recent criteria proposed by the American Society of Parenteral and Enteral Nutrition (ASPEN) consensus. Prevention is critical in avoiding the life-threatening complications of refeeding syndrome. Univariate, unadjusted long-term survival analysis revealed that lower MRA and lower SMI were associated with shorter survival (P=0.03). Akgul S, Akdemir DP, Kara M, Derman O, OCetin FC, Kabbur N. The understanding of risk factors for eating disorders in male adolescents. These include: Refeeding syndrome can cause sudden and fatal complications. After removing duplicates, 975 records were screened for titles and abstracts, and then, after excluding articles not meeting the inclusion criteria, 107 full papers were assessed for eligibility and 35 articles met the criteria for the inclusion in the analysis. https://doi.org/10.1002/eat.20164. Treatment of patients with eating disorders. NICE guidelines regarding refeeding syndrome, based on a very cautious refeeding regime reaching estimated calorie and protein needs within 7 days, compared At day 10, VO2 (R=0.59, P=0.04) was correlated with GNG and VCO2 with EGP (R=0.85, P=0.00003). 2019. https://www.nice.org.uk/guidance/qs24. Part of This is unknown. Although there are some RCTs examining aspects of NG use in YP with ED the majority of studies were retrospective cohorts or case series. 2019;24(2):17998. https://doi.org/10.1136/archdischild-2016-310506. How to Gain Weight Fast: Tips to Be Safe and Healthy, Diabulimia: Why This Eating Disorder Is So Dangerous for People with Diabetes. To date, there is still no consensus regarding the RFS definition, and its incidence is therefore difficult to obtain. Quality assessment, including risk of bias, was conducted by all authors. There were no studies from Asia, South America or Africa. https://doi.org/10.1007/s40519-018-0572-4. Halse C, Broughtwood D, Clarke S, Honey A, Kohn M, Madden S. Illumating multiple perspectives: meaning of nasogastric feeding in anorexia nervosa. Akgul S, Pehlivanturk-Kizilkan M, Ors S, Derman O, Duzceker Y, Kanpur N. Type of setting for the inpatient adolescent with an eating disorder: are specialized inpatient clinics a must or will the pediatric ward do? 31 While ongoing alcohol use will place individuals at risk for ongoing phosphorus loss, abnormalities in the excretion of urinary phosphate typically resolves after a few weeks of ongoing abstinence. For this reason, acute medical intervention is often warranted in order to reduce mortality. Refeeding syndrome is a severe complication of refeeding in people with malnutrition, it includes a series of electrolyte disorders and clinical symptoms.
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